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HRID1576088

反应详情

EQUATION

反应方程式

HRID 1576088 的结构方程式

REACTANTS

反应物

2
结构：CCOC=C(C(=O)OCC)C(=O)OCC
HCID6871

Diethyl ethoxymethylenemalonate

C10H16O5

结构：Nc1ccnn1Cc1ccco1
HCID2546182

1-[(Furan-2-yl)methyl]-1H-pyrazol-5-amine

C8H9N3O

PRODUCTS

生成物

1
结构：CCOC(=O)C(=CNc1ccnn1Cc1ccco1)C(=O)OCC
HCID68131587

1,3-Diethyl 2-[[[1-(2-furanylmethyl)-1H-pyrazol-5-yl]amino]methylene]propanedioate

C16H19N3O5

PROCEDURE

实验过程

163 g of 1-(2-furyl)methyl-5-aminopyrazole (1mol) and 216 g of ethoxymethylene malonic acid diethyl ester (1 mol) are heated to 130° (bath temperature) until the theoretical amount of alcohol is distilled off. The remaining oil, [[[1-(2-furyl)methyl-5-pyrazolyl]aino]methylene]malonic acid diethyl ester, is recrystallized from methanol, yield 280 g (84%), m.p. 84°-86°.

WORKUP

后处理

  1. distillationis distilled off
  2. customThe remaining oil, [[[1-(2-furyl)methyl-5-pyrazolyl]aino]methylene]malonic acid diethyl ester, is recrystallized from methanol, yield 280 g (84%), m.p. 84°-86°