Dimethylformamide → tert-butyl N-[2-methyl-4-[3-phenylmethoxy-4-[1,1,4-trioxo-5-(2-trimethylsilylethyl)-1,2,5-thiadiazolidin-2-yl]phenyl]but-3-en-2-yl]carbamate

HRID 157658Notes

Reaction equation

HRID 157658 reaction equation
[C:30]([CH3:31])([CH3:32])([CH3:33])[O:34][C:35]([NH:36][C:37]([CH:38]=[CH2:39])([CH3:40])[CH3:41])=[O:42].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]([N:16]2[CH2:17][C:18](=[O:29])[N:19]([CH2:23][CH2:24][Si:25]([CH3:26])([CH3:27])[CH3:28])[S:20]2(=[O:21])=[O:22])[cH:11][cH:12][c:13]([I:15])[cH:14]1.[CH3:43][CH2:44][N:45]([CH2:46][CH3:47])[CH2:48][CH3:49].[O:50]=[CH:51][N:52]([CH3:53])[CH3:54]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]([N:16]2[CH2:17][C:18](=[O:29])[N:19]([CH2:23][CH2:24][Si:25]([CH3:26])([CH3:27])[CH3:28])[S:20]2(=[O:21])=[O:22])[cH:11][cH:12][c:13]([CH:39]=[CH:38][C:37]([NH:36][C:35]([O:34][C:30]([CH3:31])([CH3:32])[CH3:33])=[O:42])([CH3:40])[CH3:41])[cH:14]1

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 8471TriethylamineHCID 13294366(1,1-Dimethylallyl)carbamic acid tert-butyl esterHCID 667569375-(2-Benzyloxy-4-iodophenyl)-1,1-dioxo-2-(2-trimethylsilanylethyl)-1,2,5-thiadiazolidin-3-one

Product 1

HCID 68839887tert-butyl N-[2-methyl-4-[3-phenylmethoxy-4-[1,1,4-trioxo-5-(2-trimethylsilylethyl)-1,2,5-thiadiazolidin-2-yl]phenyl]but-3-en-2-yl]carbamate

Sources & evidence

ORD record
ord-c07c16c818034828b628ef0a85b2c006
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

Loading…