huagongshe.com
HRID1576656

反应详情

EQUATION

反应方程式

HRID 1576656 的结构方程式

REACTANTS

反应物

2
结构：CCC12CCCN3CCc4c(n(c5ccccc45)C(O)(C(=O)OC)C1)C32
HCID5668

未命名化合物

2 次

结构：CCCC[N+](CCCC)(CCCC)CCCC.[OH-]
HCID2723671

Tetrabutylammonium Hydroxide

C16H37NO

PRODUCTS

生成物

1
结构：CC[C@]12CCCN3CCc4c(n(c5ccccc45)[C@@](O)(C(=O)OC)C1)[C@@H]32
HCID15376

Vincamine

C21H26N2O3

收率 36%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CO
溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

If the isomerisation of 16-epivincamine described in Example 4 is repeated but using 177 mg. (0.5 millimole) of 16-epivincamine in 20 ml. of methanol and 130 mg. (0.2 millimole) of a 40% aqueous solution of tetrabutylammonium hydroxide (formula (I)b), and the mixture is allowed to stand for 5 hours at 25°C. 64 mg. of vincamine are obtained (yield 36%).