huagongshe.com
HRID1576778

反应详情

EQUATION

反应方程式

HRID 1576778 的结构方程式

REACTANTS

反应物

2
结构：CS(=O)(=O)O
HCID6395

Methanesulfonic acid

CH4O3S

结构：C[C@]12CC[C@@H](O)C[C@@H]1CC[C@H]1[C@@H]3CC[C@H](C(=O)CN4CCOCC4)[C@@]3(C)CC(=O)[C@@H]12
HCID86734021

未命名化合物

PRODUCTS

生成物

1
结构：CS(=O)(=O)O.C[C@]12CC[C@@H](O)C[C@@H]1CC[C@H]1[C@@H]3CC[C@H](C(=O)CN4CCOCC4)[C@@]3(C)CC(=O)[C@@H]12
HCID86734026

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCO
溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

A solution of 3α-hydroxy-21-morpholino-5α-pregnane-11,20dione (167 mg., 0.4 mmole) in ethanol (2 ml.) was treated with 0.204 N aqueous solution of methanesulphonic acid (3.92 ml. 0.8 mmole). The resulting solution was evaporated under vacuum and then treated with water (5 ml.). The undissolved solid (14.7 mg.) was removed by filtration and the filtrate was made up to 15.23 ml. with distilled water thereby obtaining a 1% aqueous solution of the title compound.

WORKUP

后处理

  1. customThe resulting solution was evaporated under vacuum
  2. additiontreated with water (5 ml.)
  3. customThe undissolved solid (14.7 mg.) was removed by filtration