huagongshe.com
HRID1576783

反应详情

EQUATION

反应方程式

HRID 1576783 的结构方程式

REACTANTS

反应物

2
结构：O=C1O[C@H]([C@@H](O)CO)C(O)=C1O
HCID54670067

L-Ascorbic acid

C6H8O6

结构：CCO[C@H]1C[C@@]2(C)[C@@H](CC[C@H]3[C@@H]4CC[C@H](C(=O)CN5CCOCC5)[C@@]4(C)CC(=O)[C@@H]32)C[C@@H]1O
HCID86734023

未命名化合物

PRODUCTS

生成物

1
结构：CCO[C@H]1C[C@@]2(C)[C@@H](CC[C@H]3[C@@H]4CC[C@H](C(=O)CN5CCOCC5)[C@@]4(C)CC(=O)[C@@H]32)C[C@@H]1O.O=C1O[C@H]([C@@H](O)CO)C([O-])=C1O
HCID178468151

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCO
溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

A solution of 2β-Ethoxy-3α-hydroxy-21-morpholino-5α-pregnane-11,20-dione (116 mg; 0.25 mmole) in ethanol (2 ml.) was treated with an 0.1N aqueous solution of ascorbic acid (2.5 ml; 0.25 mmole) and the resulting solution was evaporated under vacuum. The residue was dissolved in water (ca. 5 ml.) and clarified by filtration. The filtrate was diluted to 11.6 ml. with distilled water, thereby giving a 1% aqueous solution of the title compound.

WORKUP

后处理

  1. customthe resulting solution was evaporated under vacuum
  2. dissolutionThe residue was dissolved in water (ca. 5 ml.)
  3. filtrationclarified by filtration
  4. additionThe filtrate was diluted to 11.6 ml