反应详情

A mixture of 18.8 g (0.05 mole) of 2,7-bis(4-chlorobutyryl)fluorene, 34.0 g (0.4 mole) of piperidine, and 16.6 g (0.1 mole) of potassium iodide in 200 ml of butanone is stirred and refluxed for 3 days. The reaction mixture is poured into 1000 ml of water, and the solid which precipitates is filtered and recrystallized twice from chloroform-acetone to give the desired 2,7-bis(4-piperidinobutyryl)fluorene as the free base.

1. temperaturerefluxed for 3 days
2. customthe solid which precipitates
3. filtrationis filtered
4. customrecrystallized twice from chloroform-acetone