Ammonia → HCID 178510730, compound

HRID 1577530Notes

Reaction equation

HRID 1577530 reaction equation
[C:1]([C:9]1[S:13][C:12]2[CH:14]=[CH:15][C:16]([Cl:18])=[CH:17][C:11]=2[C:10]=1[OH:19])(=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.P(Cl)(Cl)(Cl)(Cl)Cl.[NH3:26]>C(OCC)(=O)C>[NH2:26]/[C:1](/[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)=[C:9]1\[C:10](=[O:19])[C:11]2[CH:17]=[C:16]([Cl:18])[CH:15]=[CH:14][C:12]=2[S:13]\1

Participants

5

Reactant 3

HCID 222AmmoniaHCID 24819Phosphorus pentachlorideHCID 135976158HCID 135976158, compound

Product 1

HCID 178510730HCID 178510730, compoundYield 57%

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

Prepared as in Example 1 from 2-benzoyl-5-chloro-benzo[b]-thiophen-3-ol, phosphorus(V) chloride and concentrated ammonia with a yield of 57% of theory. M.p. 172°-173° C. (ethyl acetate)

Sources & evidence

ORD record
ord-e0b06f1af3904ad980b99d6a0cf52e2f
Source dataset
uspto-grants-1981_09
Patent number
US04288437

Reaction notes

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