Tetrahydrofuran → HCID 70547117, compound

HRID 1577939Notes

Reaction equation

HRID 1577939 reaction equation
C[C:2]([O-])([CH3:4])[CH3:3].[K+].[CH:7]1([CH:13]=[CH:14][CH2:15][N:16]=C)CCCCC1.O1C[CH2:21][CH2:20][CH2:19]1>>[CH:14](=[CH:15][N:16]=[C:3]1[CH2:2][CH2:4][CH2:21][CH2:20][CH2:19]1)[CH2:13][CH3:7]

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 23665647Potassium tert-butoxideHCID 70547811HCID 70547811, compound

Product 1

HCID 70547117HCID 70547117, compoundYield 83%

Procedure

The procedure is carried out as described in Example 1, with the use however in this case of 5 g of potassium tert-butylate, 240 g (1.59 mols) of cyclohexyl-methylidene-allylamine and 250 ml of tetrahydrofuran. After a reaction time of 1 hour at 30° C., there is obtained 199 g (1.32 mols) of propylidene(cyclohexylidene-methylamine), corresponding to a yield of 83% of theory; b.p. 51°-53° C./0.3 Torr; nD20 =1.5072.

Sources & evidence

ORD record
ord-0610e8bd3a6f47f3afa57ea7265169d0
Source dataset
uspto-grants-1981_09
Patent number
US04289905

Reaction notes

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