Iodoethane → HCID 178477458, compound

HRID 1578047Notes

Reaction equation

HRID 1578047 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([Cl:8])[C:3]=1[NH:9][C:10]([NH:12][C:13](=[O:15])[CH3:14])=[S:11].C(=O)([O-])[O-].[K+].[K+].[CH2:22](I)[CH3:23]>CC(C)=O>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([Cl:8])[C:3]=1[NH:9][C:10](=[N:12][C:13](=[O:15])[CH3:14])[S:11][CH2:22][CH3:23]

Participants

5

Reactant 3

HCID 6340IodoethaneHCID 11430Potassium CarbonateHCID 12952276HCID 12952276, compound

Product 1

HCID 178477458HCID 178477458, compoundYield 56%

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

7.9 g (0.03 M) of N-(2,6-dichlorophenyl)-N'-acetylthiourea, 3.0 g (0.022 M) of ground potassium carbonate, 3.0 ml (0.04 M) of ethyliodide and 100 ml of acetone are mixed and then boiled for 5 hours. The acetone then is distilled off. The residue is washed with water and filtered. 6.8 g (80.5 % of the theoretical yield) of N-(2,6-dichlorophenyl)-N'-acetyl-S-ethylisothiourea with a melting point of 97°-100° are obtained. After recrystallization from ethyl alcohol the product has a melting point of 99°-102° C. The yield is 56 % of the theoretical one.

Workup

  1. distillationThe acetone then is distilled off
  2. washThe residue is washed with water
  3. filtrationfiltered

Sources & evidence

ORD record
ord-364c77e6ebfd4b8f987ccd8defc3bbe6
Source dataset
uspto-grants-1981_09
Patent number
US04290971

Reaction notes

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