2-Chloroethanol → 2-Chloroethyl 2-methylpropane-1-sulfonate

HRID 1579131Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1579131
[CH2:1]([Cl:4])[CH2:2][OH:3].CCOCC.[CH2:10]([S:14](Cl)(=[O:16])=[O:15])[CH:11]([CH3:13])[CH3:12]>C(N(CC)CC)C>[CH2:10]([S:14]([O:3][CH2:2][CH2:1][Cl:4])(=[O:16])=[O:15])[CH:11]([CH3:13])[CH3:12]

Komponenten

5

Edukt 3

HCID 342-ChloroethanolHCID 3283Diethyl EtherHCID 1822361-Propanesulfonyl chloride, 2-methyl-

Produkt 1

HCID 227699422-Chloroethyl 2-methylpropane-1-sulfonate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8471TriethylamineLösungsmittel

Reaktionsbedingungen

Temperatur
23 °C

Versuchsvorschrift

A mixture was formed containing 6.7 ml. of ethylene chlorohydrin, 70 ml. of ether and 15.6 g. of isobutane sulfonyl chloride. Then, 14 ml. of triethylamine was added dropwise to the mixture with stirring in an ice bath over a period of 30 minutes at 12°-14°C. While stirring the mixture was allowed to warm to 23°C. (1 hour) and was then washed with water (100 ml.), dried over magnesium sulfate and evaporated to yield 19.7 g. of a colorless oil. nD30 1.4502.

Aufarbeitung

  1. customA mixture was formed
  2. additioncontaining 6.7 ml
  3. stirringWhile stirring the mixture
  4. washwas then washed with water (100 ml.)
  5. dry with materialdried over magnesium sulfate
  6. customevaporated
  7. customto yield 19.7 g

Quellen und Nachweise

ORD-Eintrag
ord-8c30e9d78f1e43828e8232f5813af391
Quelldatensatz
uspto-grants-1976_01
Patentnummer
US03930839

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