Hydrogen Bromide → HCID 21567169, compound

HRID 1579139Notes

Reaction equation

[N+:1]([C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[CH:7][N:8]=[CH:9]2)([O-])=O.NC1C=CC=C2C=1C=CN=C2.Br.[IH:26]>>[IH:26].[IH:26].[NH2:1][C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[CH:7][N:8]=[CH:9]2

Participants

Reactant 4

HCID 260Hydrogen Bromide

HCID 24841Hydrogen iodide

HCID 690855-Nitroisoquinoline

HCID 707665-Aminoisoquinoline

Product 1

HCID 21567169HCID 21567169, compound

Procedure

was prepared by the procedure of Example 29 hereinabove, except that the 5-nitro-isoquinoline of that example was replaced by 5-amino-isoquinoline, and the hydrogen bromide was replaced with hydrogen iodide to yield 5-aminoisoquinoline dihydro-iodide melting over the temperature range 184°C to 193°C.

Sources & evidence

ORD record: ord-97d012347a964bdfac785efe99feeadd
Source dataset: uspto-grants-1976_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US03930837

Reaction notes

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