Methanol → 6-amino-N-(5-benzylthiophen-2-ylmethyl)-nicotinamide
Reaction equation
[CH2:11]([c:12]1[cH:13][cH:14][cH:15][cH:16][cH:17]1)[c:18]1[cH:19][cH:20][c:21]([CH2:23][NH2:24])[s:22]1.[CH3:52][N:53]([CH3:54])[CH:55]=[O:56].[CH3:57][OH:58].[CH3:59][CH2:60][O:61][C:62](=[O:63])[CH3:64].[NH2:1][c:2]1[n:3][cH:4][c:5]([C:6](=[O:7])[OH:8])[cH:9][cH:10]1.[OH2:51].[P-:25]([F:26])([F:27])([F:28])([F:29])([F:30])[F:31].[n:32]1([P+:33]([N:34]([CH3:35])[CH3:36])([N:37]([CH3:38])[CH3:39])[N:40]([CH3:41])[CH3:42])[c:43]2[cH:44][cH:45][cH:46][cH:47][c:48]2[n:49][n:50]1>>[NH2:1][c:2]1[n:3][cH:4][c:5]([C:6](=[O:8])[NH:24][CH2:23][c:21]2[cH:20][cH:19][c:18]([CH2:11][c:12]3[cH:13][cH:14][cH:15][cH:16][cH:17]3)[s:22]2)[cH:9][cH:10]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-73c3b7280730486ab409b41f73d2592b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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