Sodium Azide → HCID 54294797, compound

HRID 1579434Notes

Reaction equation

HRID 1579434 reaction equation
CS(O[C@H:6]1[C:23]2[C@:18]([CH3:25])([CH:19]=[CH:20][C:21](=[O:24])[CH:22]=2)[C@@H:17]2[C@H:8]([C@H:9]3[C@@:13]([CH2:15][CH2:16]2)([CH3:14])[C:12](=[O:26])[CH2:11][CH2:10]3)[C@H:7]1OS(C)(=O)=O)(=O)=O.[N-:32]=[N+:33]=[N-:34].[Na+]>CN(C)C=O>[N:32]([C:6]1[C:23]2[C@:18]([CH3:25])([CH:19]=[CH:20][C:21](=[O:24])[CH:22]=2)[C@@H:17]2[C@H:8]([C@H:9]3[C@@:13]([CH2:15][CH2:16]2)([CH3:14])[C:12](=[O:26])[CH2:11][CH2:10]3)[CH:7]=1)=[N+:33]=[N-:34]

Participants

4

Reactant 2

HCID 33557Sodium AzideHCID 86732879HCID 86732879, compound

Product 1

HCID 54294797HCID 54294797, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

In a manner similar to that described in Example 1D, treat 6β,7β-dimethanesulfonyloxy-1,4-androstadiene-3,17-dione with sodium azide in dimethylformamide. Isolate and purify the resultant product in a manner similar to that described to obtain 6-azido-1,4,6-androstatriene-3,17-dione.

Workup

  1. customIsolate
  2. custompurify the resultant product in a manner similar to

Sources & evidence

ORD record
ord-97e55c828abb40e58cda910f1bad373e
Source dataset
uspto-grants-1976_01
Patent number
US03931167

Reaction notes

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