Hydrogen Bromide → HCID 21490323, compound

HRID 1579532Notes

Reaction equation

HRID 1579532 reaction equation
[NH2:1][C:2]1[C:10]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=2[Cl:18])([OH:11])[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([Cl:19])[CH:8]=2)[N:3]=1.Br[CH2:21][CH2:22][CH2:23][CH2:24]Br.Br>>[Cl:19][C:7]1[CH:6]=[CH:5][C:4]2[N:3]3[CH2:21][CH2:22][CH2:23][CH2:24][N:1]=[C:2]3[C:10]([C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=3[Cl:18])([OH:11])[C:9]=2[CH:8]=1

Participants

4

Reactant 3

HCID 260Hydrogen BromideHCID 80561,4-DibromobutaneHCID 21568706HCID 21568706, compound

Product 1

HCID 21490323HCID 21490323, compoundYield 24.1%

Procedure

2-Amino-5-chloro-3-(o-chlorophenyl)-3H-indol-3-ol (5.86 g) was heated under reflux with 1,4-dibromobutane (4.32 g) for 18 hours. On cooling the hydrobromide of the title compound (1.67 g) was deposited m.p. 295°-300°C (decomp.).

Sources & evidence

ORD record
ord-59b1481c0ce04a0986037046fa5963d9
Source dataset
uspto-grants-1976_01
Patent number
US03931226

Reaction notes

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