Lithium Bromide → HCID 21568952, compound

HRID 1579629Notes

Reaction equation

HRID 1579629 reaction equation
[CH3:1][C:2]1[C:10]2[O:11][C:12]([C:14]([OH:16])=[O:15])=[CH:13][C:9]=2[C:8]2[CH2:7][C:6](Br)([CH:17]([CH3:19])[CH3:18])[C:5](=[O:21])[C:4]=2[C:3]=1[CH3:22].[Br-].[Li+]>CN(C)C=O>[CH3:1][C:2]1[C:10]2[O:11][C:12]([C:14]([OH:16])=[O:15])=[CH:13][C:9]=2[C:8]2[CH2:7][C:6](=[C:17]([CH3:18])[CH3:19])[C:5](=[O:21])[C:4]=2[C:3]=1[CH3:22]

Participants

4

Reactant 2

HCID 82050Lithium BromideHCID 215689584,5-dimethyl-6-oxo-7,8-dihydro-7-bromo-7-isopropyl-6H-indeno[5,4-b]furan-2-carboxylic acid

Product 1

HCID 21568952HCID 21568952, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

A solution of 4,5-dimethyl-6-oxo-7,8-dihydro-7-bromo-7-isopropyl-6H-indeno[5,4-b]furan-2-carboxylic acid (0.01 mole) and lithium bromide (0.02 mole) in dimethylformamide (100 ml.) is heated in an inert atmosphere (nitrogen) at 95°C. for 2.0 hours; poured into ice water (300 ml.) to afford 4,5-dimethyl-6-oxo-7,8-dihydro-7-isopropylidene-6H-indeno[5,4-b]furan-2-carboxylic acid.

Sources & evidence

ORD record
ord-d2c24affff2a4e3da638b876875db4a4
Source dataset
uspto-grants-1976_01
Patent number
US03931239

Reaction notes

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