Water → HCID 53812515, compound

HRID 1579638Notes

Reaction equation

HRID 1579638 reaction equation
[CH3:1][C:2]1[C:10]2[O:11][C:12]([C:14]([OH:16])=[O:15])=[CH:13][C:9]=2[C:8]2[CH2:7][C:6](Br)([CH2:17][CH2:18][CH3:19])[C:5](=[O:21])[C:4]=2[C:3]=1[CH3:22].[Br-].[Li+].O>CN(C)C=O>[CH3:1][C:2]1[C:10]2[O:11][C:12]([C:14]([OH:16])=[O:15])=[CH:13][C:9]=2[C:8]2[CH2:7][C:6](=[CH:17][CH2:18][CH3:19])[C:5](=[O:21])[C:4]=2[C:3]=1[CH3:22]

Participants

5

Reactant 3

HCID 962WaterHCID 82050Lithium BromideHCID 12741937HCID 12741937, compound

Product 1

HCID 53812515HCID 53812515, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

A stirred solution of 4,5-dimethyl-6-oxo-7-bromo-7-propyl-7,8-dihydro-6H-indeno[5,4-b]furan-2-carboxylic acid (0.8 g., 0.0022 mole) and anhydrous lithium bromide (0.49 g., 0.0056 mole) in dimethylformamide (10 ml.) is heated at 95° in an inert atomosphere for one hour then poured into water (100 ml.) affording 4,5-dimethyl-6-oxo-7-propylidene-7,8-dihydro-6H-indeno-[5,4-b]furan-2-carboxylic acid which melts at 301°C after recrystallization from ethanol.

Sources & evidence

ORD record
ord-4895a119fa094e979f104ae2f66f5bd5
Source dataset
uspto-grants-1976_01
Patent number
US03931239

Reaction notes

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