Water → 3-Methyl-5-(2,6,6-trimethylcyclohex-2-en-1-yl)-1,2-oxazole

HRID 1579755Notes

Reaction equation

HRID 1579755 reaction equation
[CH3:1][C:2]1[CH:3]([CH:10]2[O:16][CH:11]2[C:12](=[N:14]O)[CH3:13])[C:4]([CH3:9])([CH3:8])[CH2:5][CH2:6][CH:7]=1.C1(C)C=CC(S(O)(=O)=O)=CC=1.O>C1C=CC=CC=1>[CH3:13][C:12]1[CH:11]=[C:10]([CH:3]2[C:4]([CH3:8])([CH3:9])[CH2:5][CH2:6][CH:7]=[C:2]2[CH3:1])[O:16][N:14]=1

Participants

5

Reactant 3

HCID 962WaterHCID 6101p-Toluenesulfonic acidHCID 86732896HCID 86732896, compound

Product 1

HCID 30160563-Methyl-5-(2,6,6-trimethylcyclohex-2-en-1-yl)-1,2-oxazole

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

54 g of 4-[2,6,6-trimethyl-cyclohex-2-en-1-yl]-3,4-epoxy-2-butanone-oxime, which can be prepared as indicated above, in 500 ml of benzene were refluxed in the presence of 2 g of p-toluenesulphonic acid for about 4 hours. The water formed in the course of the reaction was removed as it formed by azeotropic distillation.

Workup

  1. customwas removed as it
  2. customformed by azeotropic distillation

Sources & evidence

ORD record
ord-b2d2b942c7f34a4097ace64b60fbe746
Source dataset
uspto-grants-1976_01
Patent number
US03931323

Reaction notes

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