Sodium Iodide → HCID 21569111, compound

HRID 1579835Notes

Reaction equation

HRID 1579835 reaction equation
Br[CH:2]([C:8]1[CH:17]=[CH:16][C:15]2[C:10](=[CH:11][CH:12]=[C:13]([O:18][CH3:19])[CH:14]=2)[CH:9]=1)[C:3]([O:5][CH2:6][CH3:7])=[O:4].[I-:20].[Na+]>CC(C)=O>[I:20][CH:2]([C:8]1[CH:17]=[CH:16][C:15]2[C:10](=[CH:11][CH:12]=[C:13]([O:18][CH3:19])[CH:14]=2)[CH:9]=1)[C:3]([O:5][CH2:6][CH3:7])=[O:4]

Participants

4

Reactant 2

HCID 5238Sodium IodideHCID 21569099HCID 21569099, compound

Product 1

HCID 21569111HCID 21569111, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A mixture of 0.1 moles of ethyl α-bromo-6-methoxy-2-naphthylacetate and 150 g. of sodium iodide in 1 liter of anhydrous acetone is refluxed for 4 hours. The reaction mixture is then evaporated to dryness and extracted with ether. The ether is then washed with water, dried and evaporated to dryness to obtain ethyl α-iodo-6-methoxy-2-naphthylacetate.

Workup

  1. customThe reaction mixture is then evaporated to dryness
  2. extractionextracted with ether
  3. washThe ether is then washed with water
  4. customdried
  5. customevaporated to dryness

Sources & evidence

ORD record
ord-a4dde2ca43fa468994c7bd2b17823ab8
Source dataset
uspto-grants-1976_01
Patent number
US03931269

Reaction notes

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