Hydrochloric Acid → HCID 178522696, compound

HRID 1580069Notes

Reaction equation

HRID 1580069 reaction equation
C([O:3][CH2:4][CH2:5][O:6][C:7]1[C:24]2[C:19](=[CH:20][CH:21]=[CH:22][CH:23]=2)[N:18]=[C:9]([C:10]([NH:12][C:13]2[NH:17][N:16]=[N:15][N:14]=2)=[O:11])[CH:8]=1)=O.Cl>O.[OH-].[Na+]>[OH:3][CH2:4][CH2:5][O:6][C:7]1[C:24]2[C:19](=[CH:20][CH:21]=[CH:22][CH:23]=2)[N:18]=[C:9]([C:10]([NH:12][C:13]2[NH:17][N:16]=[N:15][N:14]=2)=[O:11])[CH:8]=1

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 178525604HCID 178525604, compound

Product 1

HCID 178522696HCID 178522696, compound

Reagents, catalysts & solvents 2

HCID 962WaterSolventHCID 14798Sodium HydroxideSolvent

Procedure

4(2-Formyloxyethoxy)-N(1H-tetrazol-5-yl)quinaldamide (2 g) in water (100 ml) and 2N sodium hydroxide (14 ml) was warmed on a steam bath for 15 minutes, and cooled. The solution was acidified to pH 2 with dilute hydrochloric acid. The solid was collected, crystallised from aqueous dimethylformamide and dried, m.p. 261.5°-262° (d).

Workup

  1. temperaturecooled
  2. customThe solid was collected
  3. customcrystallised from aqueous dimethylformamide
  4. customdried

Sources & evidence

ORD record
ord-8dbe606df59642c3b678539d90e6f3a6
Source dataset
uspto-grants-1976_01
Patent number
US03932416

Reaction notes

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