Sodium ethoxide → HCID 12772779, compound

HRID 1580302Notes

Reaction equation

HRID 1580302 reaction equation
Cl[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[S:8][CH3:9].[O-:10][CH2:11][CH3:12].[Na+]>[N+](C1C=CC=CC=1)([O-])=O.[Cu]>[CH2:11]([O:10][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[S:8][CH3:9])[CH3:12]

Participants

5

Reactant 2

HCID 2723922Sodium ethoxideHCID 27373632-Chlorophenyl methyl sulfide

Product 1

HCID 12772779HCID 12772779, compound

Reagents, catalysts & solvents 2

HCID 23978CopperCatalystHCID 7416NitrobenzeneSolvent

Procedure

o-Chlorothioanisole (prepared by the procedure of Example 5-A (15.85 g., 0.1 mole) is stirred at reflux in nitrobenzene containing copper powder (100 mg.) and sodium ethoxide (6.8 g., 0.1 mole) for 2 hours. The product is steam distilled and the distillate dried and fractionally distilled under reduced pressure to yield o-ethoxythioanisole.

Workup

  1. distillationdistilled
  2. customthe distillate dried
  3. distillationfractionally distilled under reduced pressure

Sources & evidence

ORD record
ord-46851fe63ae0435ebb2aa5d2c718cdbc
Source dataset
uspto-grants-1976_01
Patent number
US03932498

Reaction notes

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