Benzyl Bromide → HCID 12255191, compound

HRID 1580635Notes

Reaction equation

HRID 1580635 reaction equation
[Br:1][CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[NH2:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][N:11]=1>C1(C)C(C)=CC=CC=1>[Br-:1].[NH2:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][N+:11]=1[CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1

Participants

4

Reactant 2

HCID 7498Benzyl BromideHCID 104392-Aminopyridine

Product 1

HCID 12255191HCID 12255191, compoundYield 63.9%

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Procedure

A solution of α-bromotoluene (100.0 g), 2-aminopyridine (82.0 g) and 1000 ml of xylene are heated under reflux for 7 hours to give 99.1 g of the title compound, melting point 187°-190°C.

Workup

  1. temperatureunder reflux for 7 hours

Sources & evidence

ORD record
ord-8f37d51154d7488085a0ccefe10ad9a6
Source dataset
uspto-grants-1976_01
Patent number
US03933836

Reaction notes

Loading…