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HRID1580686

反应详情

EQUATION

反应方程式

HRID 1580686 的结构方程式

REACTANTS

反应物

3
结构：CC(=O)Nc1ccc(S(=O)(=O)Cl)cc1
HCID8481

4-(Acetylamino)benzenesulfonyl chloride

C8H8ClNO3S

结构：O=C([O-])O.[Na+]
HCID516892

Sodium Bicarbonate

CHNaO3

结构：CCCCN1CCC(N)CC1
HCID12262820

1-butylpiperidin-4-amine

C9H20N2

PRODUCTS

生成物

1
结构：CCCCN1CCC(NS(=O)(=O)c2ccc(NC(C)=O)cc2)CC1
HCID21563541

N-{4-[(1-Butylpiperidin-4-yl)sulfamoyl]phenyl}acetamide

C17H27N3O3S

AUXILIARIES

试剂、催化剂与溶剂

2
结构：O
溶剂HCID962

Water

H2O

结构：ClC(Cl)Cl
溶剂HCID6212

Chloroform

CHCl3

PROCEDURE

实验过程

7.0 Grams of N-acetylsulphanilyl chloride were added in portions to a stirred, ice cooled, mixture of 4.7 grams of 4-amino-1-n-butyl piperidine and 6.3 grams of sodium bicarbonate in 75 milliliters of water and 35 milliliters of chloroform. After stirring overnight at room temperature the mixture was filtered, washed with water, and dried to give 4.2 grams of the title compound. Melting Point 174°-175°C.

WORKUP

后处理

  1. temperaturecooled
  2. filtrationwas filtered
  3. washwashed with water
  4. customdried