反应详情

15.8 g (0.1 mol) of 5-isopropoxy-3-methyl-1-penten-3-ol (produced in accordance with Example 63) and 20.0 g of mercury acetate are kept in 180 cc of ethylvinyl ether at reflux temperature during the course of 4 days. 0.9 cc of glacial acetic acid is added at 20° to the solution which has rendered turbid. 150 cc of 5% potassium carbonate solution are added after 3 hours and the mixture is extracted with hexane. The hexane extract is evaporated and the residue is heated to 165°-168° during 11/2 hours in an atmosphere of nitrogen and without further purification; the residue is subsequently distilled at reduced pressure. B.P. of 7-isopropoxy-5-methyl-4-heptenal: 70°-73°/0.8 mm. nD20 = 1.4476

1. temperatureat reflux temperature during the course of 4 days
2. extractionthe mixture is extracted with hexane
3. extractionThe hexane extract
4. customis evaporated
5. temperaturethe residue is heated to 165°-168° during 11/2 hours in an atmosphere of nitrogen
6. customwithout further purification
7. distillationthe residue is subsequently distilled at reduced pressure
8. custom70°-73°/0.8 mm