Sodium Iodide → HCID 657489, compound

HRID 1582018Notes

Reaction equation

HRID 1582018 reaction equation
[OH-].[Na+].[CH:3]1[C:15]2[NH:14][C:13]3[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=3)[C:7]=2[CH:6]=[CH:5][CH:4]=1.[Na+].[I-].Cl[CH2:19][CH2:20][O:21][CH2:22][CH2:23][O:24]C1CCCCO1>[Cl-].C([N+](CC)(CC)CC)C1C=CC=CC=1.C1C=CC=CC=1>[CH:12]1[C:13]2[N:14]([CH2:19][CH2:20][O:21][CH2:22][CH2:23][OH:24])[C:15]3[C:7](=[CH:6][CH:5]=[CH:4][CH:3]=3)[C:8]=2[CH:9]=[CH:10][CH:11]=1

Participants

7

Reactant 4

HCID 5238Sodium IodideHCID 6854CarbazoleHCID 14798Sodium HydroxideHCID 109657372-[2-(2-Chloroethoxy)ethoxy]oxane

Product 1

HCID 657489HCID 657489, compound

Reagents, catalysts & solvents 2

HCID 66133Benzyl triethylammonium chlorideCatalystHCID 241BenzeneSolvent

Procedure

To a flask containing 100 ml benzene, 100 ml 50% NaOH, was added carbazole (2) (20 g, 0.12 mmol), 4 g benzyltriethylammonium chloride (TEBA), 1 g of NaI and 2-[2-(2-chloroethoxy)-ethoxy]-tetrahydropyran (3) (38 g, 0.12 mmol) under N2. The mixture was refluxed for 6 h.

Workup

  1. temperatureThe mixture was refluxed for 6 h.

Sources & evidence

ORD record
ord-e652bf869a7c42fea8480b94f0f85f6a
Source dataset
uspto-grants-2004_05
Patent number
US06733883B2

Reaction notes

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