Propane, 2,2',2''-[methylidynetris(oxy)]tris- → HCID 22717683, compound

HRID 1582567Notes

Reaction equation

HRID 1582567 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]([CH:18]([CH3:20])[CH3:19])[C:9]([N:11]2[C:15](=[O:16])[NH:14][C:13](=[O:17])[O:12]2)=[O:10])=[CH:4][CH:3]=1.[CH:21](OC(OC(C)C)OC(C)C)([CH3:23])[CH3:22]>>[F:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]([CH:18]([CH3:20])[CH3:19])[C:9]([N:11]2[C:15](=[O:16])[N:14]([CH:21]([CH3:23])[CH3:22])[C:13](=[O:17])[O:12]2)=[O:10])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 78191Propane, 2,2',2''-[methylidynetris(oxy)]tris-HCID 22717673HCID 22717673, compound

Product 1

HCID 22717683HCID 22717683, compoundYield 86%

Procedure

A solution of the compound of Step A (1.0 g, 3.6 mmol) in 20 mL of triisopropylorthoformate was heated at 145° C. for 2 h and then allowed to stir at ambient temperature overnight. The volatiles were removed under reduced pressure, and the residue recrystallized from methanol to give 0.99 g (86%) of the title compound, a compound of this invention, as a solid melting at 78-80° C.

Workup

  1. customThe volatiles were removed under reduced pressure
  2. customthe residue recrystallized from methanol

Sources & evidence

ORD record
ord-a248a0ebe119451daa4957ee9bd13dcd
Source dataset
uspto-grants-2004_05
Patent number
US06737383B1

Reaction notes

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