4-Methoxybenzylamine → HCID 22717975, compound

HRID 1582599Notes

Reaction equation

HRID 1582599 reaction equation
[CH3:1][O:2][C:3]1[CH:10]=[CH:9][C:6]([CH2:7][NH2:8])=[CH:5][CH:4]=1>O1CCCC1>[CH3:1][O:2][C:3]1[CH:10]=[CH:9][C:6]([CH2:7][N:8]=[CH:5][CH:6]([CH3:9])[CH3:7])=[CH:5][CH:4]=1

Participants

3

Reactant 1

HCID 754524-Methoxybenzylamine

Product 1

HCID 22717975HCID 22717975, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Conditions

Temperature
60 °C

Procedure

Isobutylaldehyde (2.8 ml) was dissolved in tetrahydrofuran (10 ml), and the solution was added with 4-methoxybenzylamine (1 ml) and then stirred at 60° C. for 2 hours. The imine generation was observed by 1H-NMR, and then the reaction mixture was concentrated under reduced pressure to obtain crude (4-methoxybenzyl)-N-(2-methylpropylidene)amine.

Workup

  1. concentrationwas concentrated under reduced pressure

Sources & evidence

ORD record
ord-166ca30bc3f34d259de27537121c2bf3
Source dataset
uspto-grants-2004_05
Patent number
US06737416B2

Reaction notes

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