Hydrochloric Acid → HCID 13506753, compound

HRID 1583390Notes

Reaction equation

HRID 1583390 reaction equation
[N:1]1[CH:6]=[CH:5][C:4]([C:7]2[N:12]3[CH:13]=[CH:14][N:15]=[C:11]3[N:10]=[CH:9][CH:8]=2)=[CH:3][CH:2]=1.[ClH:16]>C(OC(OCC)OCC)C>[ClH:16].[N:1]1[CH:2]=[CH:3][C:4]([C:7]2[N:12]3[CH:13]=[CH:14][N:15]=[C:11]3[N:10]=[CH:9][CH:8]=2)=[CH:5][CH:6]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 13506752HCID 13506752, compound

Product 1

HCID 13506753HCID 13506753, compound

Reagents, catalysts & solvents 1

HCID 31214Ethyl orthoformateSolvent

Procedure

A 2.0 g amount of 5-(4-pyridyl)imidazo[1,2-a]pyrimidine was suspended in 100 ml of triethylorthoformate and 1.67 ml of concentrated hydrochloric acid was added. After standing at room temperature for 6 hours the resultant precipitate was collected by filtration and gave 0.47 g of the product of the Example as a yellow solid, mp 295°-300° C.(dec.).

Workup

  1. filtrationthe resultant precipitate was collected by filtration

Sources & evidence

ORD record
ord-80284bac25664b10bc5095acee8f668a
Source dataset
uspto-grants-1985_11
Patent number
US04551530

Reaction notes

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