反应详情

A mixture of 3-fluoro-4-(5-methyl-2-phenyl-4-oxazolylmethoxy)nitrobenzene (13.6 g), palladium-carbon (5%, 2.0 g) and tetrahydrofuran (THF) (200 ml) was subjected to catalytic hydrogenation under 1 atmospheric pressure at room temperature. The catalyst was filtered off, and the filtrate was concentrated under reduced pressure to yield 3-fluoro-4-(5-methyl-2-phenyl-4-oxazolylmethoxy)aniline as an oily product.

1. customwas subjected to catalytic hydrogenation under 1 atmospheric pressure at room temperature
2. filtrationThe catalyst was filtered off
3. concentrationthe filtrate was concentrated under reduced pressure