Hydrochloric Acid → rac-(2'S,3'R,4'S,5'R)-6-chloro-4'-(3-chloro-2-fluoro-phenyl)-2'-(2,2-dimethyl-propyl)-2-oxo-1,2-dihydro-spiro[indole-3,3'-pyrrolidine]-5'-carboxylic acid [1-(2-hydroxy-ethyl)-1H-pyrazol-3-yl]-amide
Reaction equation
[C:1]([Si:2]([CH3:3])([CH3:4])[O:6][CH2:7][CH2:8][n:9]1[n:10][c:11]([NH:14][C:15](=[O:16])[CH:17]2[CH:18]([c:37]3[c:38]([F:44])[c:39]([Cl:43])[cH:40][cH:41][cH:42]3)[C:19]3([C:20](=[O:29])[NH:21][c:22]4[cH:23][c:24]([Cl:28])[cH:25][cH:26][c:27]43)[CH:30]([CH2:32][C:33]([CH3:34])([CH3:35])[CH3:36])[NH:31]2)[cH:12][cH:13]1)([CH3:5])([CH3:45])[CH3:46].[ClH:47].[O:48]1[CH2:49][CH2:50][CH2:51][CH2:52]1>>[OH:6][CH2:7][CH2:8][n:9]1[n:10][c:11]([NH:14][C:15](=[O:16])[CH:17]2[CH:18]([c:37]3[c:38]([F:44])[c:39]([Cl:43])[cH:40][cH:41][cH:42]3)[C:19]3([C:20](=[O:29])[NH:21][c:22]4[cH:23][c:24]([Cl:28])[cH:25][cH:26][c:27]43)[CH:30]([CH2:32][C:33]([CH3:34])([CH3:35])[CH3:36])[NH:31]2)[cH:12][cH:13]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-8233ecdb79514c2a93f6e622347b1aaf
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
Loading…