Allyl Mercaptan → HCID 9881434, compound

HRID 1585993Notes

Reaction equation

HRID 1585993 reaction equation
[Na].[CH2:2]([SH:5])[CH:3]=[CH2:4].[CH2:6]([O:8][C:9]1[C:18]2[CH2:17][CH2:16][CH2:15][CH2:14][C:13]=2[C:12](Cl)=[N:11][N:10]=1)[CH3:7]>CO>[CH2:6]([O:8][C:9]1[C:18]2[CH2:17][CH2:16][CH2:15][CH2:14][C:13]=2[C:12]([S:5][CH2:2][CH:3]=[CH2:4])=[N:11][N:10]=1)[CH3:7]

Participants

5

Reactant 3

HCID 13367Allyl MercaptanHCID 5360545SodiumHCID 21217659HCID 21217659, compound

Product 1

HCID 9881434HCID 9881434, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

0.23 g(0.01 mol) of metallic sodium was dissolved in 100 ml of absolute methanol and then mixed with 0.93 ml (0.01 mol) of allylmercaptan. To this mixture was added 2.13 g(0.01 mol) of 1-ethoxy-4-chloro-5,6,7,8-tetrahydro-phthalazine obtained from Preparation 9. The reaction solution was refluxed for 3 hours and then treated according to the same manner as Example 1 to obtain the title compound as a freezing white crystal.

Workup

  1. customobtained from Preparation 9
  2. temperatureThe reaction solution was refluxed for 3 hours
  3. additiontreated

Sources & evidence

ORD record
ord-a6ed875bffbc4c9db3a7a28915d5e7b5
Source dataset
uspto-grants-1999_08
Patent number
US05942511

Reaction notes

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