Acetonitrile → (9-(3-(2-Hydroxyethyl)benzyl)-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl)(2-(trifluoromethyl)thiazol-4-yl)methanone
Reaction equation
[Br:1][CH2:2][c:3]1[cH:4][c:5]([CH2:9][CH2:10][OH:11])[cH:6][cH:7][cH:8]1.[CH3:41][CH2:42][N:43]([CH2:44][CH3:45])[CH2:46][CH3:47].[CH3:48][C:49]#[N:50].[F:12][C:13]([F:14])([F:15])[C:16]([OH:17])=[O:18].[O:19]1[CH2:20][CH2:21][N:22]([C:30](=[O:31])[c:32]2[n:33][c:34]([C:37]([F:38])([F:39])[F:40])[s:35][cH:36]2)[CH2:23][C:24]12[CH2:25][CH2:26][NH:27][CH2:28][CH2:29]2>>[CH2:2]([c:3]1[cH:4][c:5]([CH2:9][CH2:10][OH:11])[cH:6][cH:7][cH:8]1)[N:27]1[CH2:26][CH2:25][C:24]2([O:19][CH2:20][CH2:21][N:22]([C:30](=[O:31])[c:32]3[n:33][c:34]([C:37]([F:38])([F:39])[F:40])[s:35][cH:36]3)[CH2:23]2)[CH2:29][CH2:28]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-0e0f203aa90646a4b46731c775938590
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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