Hydrochloric Acid → HCID 15484978, compound

HRID 1586850Notes

Reaction equation

HRID 1586850 reaction equation
[CH:1]1([S:6]([NH2:9])(=[O:8])=[O:7])[CH2:5][CH2:4][CH2:3][CH2:2]1.[OH-].[Na+].[Cl:12][C:13]1[CH:14]=[C:15]([N:20]=[C:21]=[O:22])[CH:16]=[CH:17][C:18]=1[Cl:19].Cl>CC(C)=O.O>[Cl:12][C:13]1[CH:14]=[C:15]([NH:20][C:21]([NH:9][S:6]([CH:1]2[CH2:5][CH2:4][CH2:3][CH2:2]2)(=[O:8])=[O:7])=[O:22])[CH:16]=[CH:17][C:18]=1[Cl:19]

Participants

7

Reactant 4

HCID 313Hydrochloric AcidHCID 76073,4-Dichlorophenyl isocyanateHCID 14798Sodium HydroxideHCID 4645983Cyclopentanesulfonamide

Product 1

HCID 15484978HCID 15484978, compoundYield 85.2%

Reagents, catalysts & solvents 2

HCID 180AcetoneSolvent2×HCID 962WaterSolvent

Procedure

The general method of procedure A was followed with cyclopentanesulfonamide (3 g), acetone (200 ml), 1N sodium hydroxide (20 ml), and 3,4-dichlorophenyl isocyanate (3.6 g) dissolved in acetone (50 ml). After two hours, 1N HCl (20 ml) was added and the resulting solid diluted with water and collected. After drying at 5° C., 5.5 g of solid product were obtained.

Workup

  1. customcollected
  2. customAfter drying at 5° C.

Sources & evidence

ORD record
ord-f99622174c57423e97f5616f7ae57be9
Source dataset
uspto-grants-1993_06
Patent number
US05216026

Reaction notes

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