Hydrochloric Acid → 4-(4-Fluorophenyl)piperidin-3-ol
Reaction equation
[B:21]([OH:22])([OH:23])[OH:24].[BH4-:15].[CH2:25]([CH2:26][O:27][CH3:28])[O:29][CH3:30].[ClH:1].[F:2][c:3]1[cH:4][cH:5][c:6]([C:9]2=[CH:14][CH2:13][NH:12][CH2:11][CH2:10]2)[cH:7][cH:8]1.[K+:18].[Na+:16].[OH-:17].[OH2:31].[OH:19][OH:20]>>[F:2][c:3]1[cH:4][cH:5][c:6]([CH:9]2[CH2:10][CH2:11][NH:12][CH2:13][CH:14]2[OH:22])[cH:7][cH:8]1Participants
11
Reactant 10
Product 1
Sources & evidence
- ORD record
- ord-16487da94818415f9c76163912d36b15
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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