Benzyl Bromide → HCID 86746953, compound

HRID 1587750Notes

Reaction equation

HRID 1587750 reaction equation
[C:1](=[N:9][OH:10])([C:3]1[CH:4]=[N:5][CH:6]=[CH:7][CH:8]=1)[CH3:2].[CH2:11]([Br:18])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>C(O)C>[Br-:18].[CH2:11]([N:5]1[CH:6]=[CH:7][CH:8]=[C:3]([C:1](=[N:9][OH:10])[CH3:2])[CH2:4]1)[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1

Participants

4

Reactant 2

HCID 7498Benzyl BromideHCID 222791-(3-Pyridinyl)ethanone oxime

Product 1

HCID 86746953HCID 86746953, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

7.4 g of 3-acetylpyridine oxime is dissolved in 80 cm3 of ethanol, 8 cm3 of benzyl bromide is added to it, with heating at reflux for 6 hours. The solvent is eliminated followed by crystallization from an ether/methanol mixture. 14.21 g of the expected product is obtained. m.p.=200°-201° C.

Workup

  1. temperaturewith heating
  2. temperatureat reflux for 6 hours
  3. customThe solvent is eliminated followed by crystallization from an ether/methanol mixture

Sources & evidence

ORD record
ord-29a5bf5551d24054bc0acb824680845c
Source dataset
uspto-grants-1993_06
Patent number
US05219873

Reaction notes

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