Potassium Chloride → Citrate

HRID 1587885Notes

Reaction equation

[Cl-].[K+].[C:3]([O-:15])(=[O:14])[CH2:4][C:5]([CH2:10][C:11]([O-:13])=[O:12])([C:7]([O-:9])=[O:8])[OH:6].[K+].[K+].[K+].C([O-])(=O)CC(CC([O-])=O)(C([O-])=O)O.[Mg+2:32].C([O-])(=O)CC(CC([O-])=O)(C([O-])=O)O.[Mg+2].[Mg+2].C([O-])(=O)CC(CC([O-])=O)(C([O-])=O)O.[Mg+2].[K+].[K]>>[Mg:32].[C:3]([O-:15])(=[O:14])[CH2:4][C:5]([CH2:10][C:11]([O-:13])=[O:12])([C:7]([O-:9])=[O:8])[OH:6]

Participants

Reactant 5

HCID 4873Potassium Chloride

HCID 13344Tripotassium citrate

HCID 5462222Potassium

HCID 6099959Trimagnesium dicitrate

HCID 21986909Potassium-magnesium citrate2×

Product 2

HCID 31348Citrate

HCID 5462224Magnesium

Procedure

Each patient underwent five phases of study: placebo, potassium chloride, potassium citrate, magnesium citrate, and potassium-magnesium citrate. The results (mean values for the two patients) are outlined in Table 1. Compared to potassium chlorlde, potassium magnesium citrate gave a higher urinary pH, magnesium, and citrate. Compared to potassium citrate, potassium magnesium citrate produced a greater citrate excretion as magnesium citrate, potassium magnesium citrate gave higher values for urinary pH and citrate. Finally, compared to the placebo, potassium magnesium citrate produced higher values for urinary pH, magnesium, potassium and citrate, and lower values for urinary calcium and oxalate.

Workup

customThe results (mean values for the two patients)

Sources & evidence

ORD record: ord-2c227474983549019c6d56590d2fca9f
Source dataset: uspto-grants-1993_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05219889

Reaction notes

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