Azidotrimethylsilane → HCID 57066699, compound

HRID 1587993Notes

Reaction equation

HRID 1587993 reaction equation
[CH3:1][O:2][CH:3]([O:10][CH3:11])[CH2:4][C@H:5]1[O:7][C@@H:6]1[CH2:8][OH:9].O(O)O.[N:15]([Si](C)(C)C)=[N+:16]=[N-:17].[F-].C([Al+]CC)C>ClCCl>[N:15]([C@@H:5]([CH2:4][CH:3]([O:10][CH3:11])[O:2][CH3:1])[C@H:6]([OH:7])[CH2:8][OH:9])=[N+:16]=[N-:17]

Participants

5

Reactant 3

HCID 78378AzidotrimethylsilaneHCID 16688914367-44-2HCID 86746974HCID 86746974, compound

Product 1

HCID 57066699HCID 57066699, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

A mixture of the epoxy alcohol (2R,3R) 3-(2,2-dimethoxyethyl)oxirane-methanol and azidotrimethylsilane in dichloromethane is reacted with diethylaluminum fluoride to obtain (2S,3S) 3-azido-5,5-dimethoxypentane1,2-diol: ##STR6##

Sources & evidence

ORD record
ord-d0a882f871a74f7bb804219f6323d5aa
Source dataset
uspto-grants-1993_06
Patent number
US05220003

Reaction notes

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