Sodium Carbonate → HCID 12011111, compound

HRID 1588087Notes

Reaction equation

HRID 1588087 reaction equation
Cl.COC1C=C2C(=CC=1)C=C(C([NH2:16])C)C=C2.[CH:17](=O)[C:18]1[CH:23]=[CH:22][C:21]([O:24][CH3:25])=[CH:20][CH:19]=1.C(=O)([O-])[O-].[Na+].[Na+]>CO>[CH:17](=[NH:16])[C:18]1[CH:23]=[CH:22][C:21]([O:24][CH3:25])=[CH:20][CH:19]=1

Participants

5

Reactant 3

HCID 10340Sodium CarbonateHCID 312444-MethoxybenzaldehydeHCID 45595268HCID 45595268, compound

Product 1

HCID 12011111HCID 12011111, compoundYield 230.8%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a solution of the amine 2.1 (2.51 g, 12.5 mmol) in 10 mL methanol were added p-anisaldehyde (1.5 mL, 12.5 mmol) and anhydrous sodium carbonate (1.3 g, 12.5 mmol). The mixture was stirred for 15 hours and was filtered through celite and concentrated to give 3.9 g of the corresponding p-anisaldehyde imine 2.2.

Workup

  1. filtrationwas filtered through celite and
  2. concentrationconcentrated

Sources & evidence

ORD record
ord-88025c7df7d14a08b720692de16b69dc
Source dataset
uspto-grants-1993_06
Patent number
US05220059

Reaction notes

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