Chloride → 4-chloro-N-{2-[(2-fluoro-6-methoxyphenyl)-hydroxy-methyl]-5-methyl-pyridin-3-yl}-N-methoxymethyl-3-trifluoromethyl-benzenesulfonamide
Reaction equation
[Br:1][c:2]1[n:3][cH:4][c:5]([CH3:26])[cH:6][c:7]1[N:8]([S:9](=[O:10])(=[O:11])[c:12]1[cH:13][c:14]([C:19]([F:20])([F:21])[F:22])[c:15]([Cl:18])[cH:16][cH:17]1)[CH2:23][O:24][CH3:25].[CH2:43]1[O:44][CH2:45][CH2:46][CH2:47]1.[CH:28]([Mg+:29])([CH3:30])[CH3:31].[Cl-:27].[F:32][c:33]1[c:34]([CH:35]=[O:36])[c:37]([O:41][CH3:42])[cH:38][cH:39][cH:40]1>>[c:2]1([CH:35]([c:34]2[c:33]([F:32])[cH:40][cH:39][cH:38][c:37]2[O:41][CH3:42])[OH:36])[n:3][cH:4][c:5]([CH3:26])[cH:6][c:7]1[N:8]([S:9](=[O:10])(=[O:11])[c:12]1[cH:13][c:14]([C:19]([F:20])([F:21])[F:22])[c:15]([Cl:18])[cH:16][cH:17]1)[CH2:23][O:24][CH3:25]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-06382569afc5463a8fbafbf201028d6b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
Loading…