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HRID1588434

反应详情

EQUATION

反应方程式

HRID 1588434 的结构方程式

REACTANTS

反应物

4
结构：O
HCID962

Water

H2O

结构：O=C([O-])[O-].[K+].[K+]
HCID11430

Potassium Carbonate

CK2O3

结构：Cl.ClCc1ccc2ccccc2n1
HCID3083823

2-(Chloromethyl)quinoline hydrochloride

C10H9Cl2N

结构：C=CCc1c(O)ccc2[nH]c3c(c12)CCCC3CC(=O)OCC
HCID19755403

未命名化合物

PRODUCTS

生成物

1
结构：C=CCc1c(OCc2ccc3ccccc3n2)ccc2[nH]c3c(c12)CCCC3CC(=O)OCC
HCID19755383

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

The compound from Step 4 (400 mg) is dissolved in 3.0 ml of DMF and 400 mg of 2-(chloromethyl)quinoline hydrochloride is added, followed by 275 mg of K2CO3. The reaction is stirred for 48 hours, 3.0 ml of H2O is added and the product extracted into Et2O. After washing with brine, the organic phase is dried and evaporated to yield ethyl 5-allyl-6-(quinolin-2-ylmethoxy)-1,2,3,4-tetrahydrocarbazol-1-ylacetate.

WORKUP

后处理

  1. extractionthe product extracted into Et2O
  2. washAfter washing with brine
  3. customthe organic phase is dried
  4. customevaporated