Urea → Hydroxyethyl imidazolidinone
Reaction equation
[OH:1][CH2:2][CH2:3][NH:4][CH2:5][CH2:6][NH2:7].N[C:9](N)=[O:10]>O>[OH:1][CH2:2][CH2:3][N:4]1[CH2:5][CH2:6][NH:7][C:9]1=[O:10]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Conditions
- Temperature
- 210 °C
Procedure
A mixture of N-(2-hydroxyethyl)ethylenediamine (31.2 g), urea (23.4 g) and water (3 ml) was heated at 130° C. for 3 hours and at 210° C. for 8 hours and then distilled directly from the reaction mixture to give 1-(2-hydroxyethyl)-2-imidazolidinone (30 g) as an oil [(b.p. 150°-160° C. (0.2 mm)] which solidified to give a solid (m.p. 50-51).
Workup
- distillationdistilled directly from the reaction mixture
Sources & evidence
- ORD record
- ord-2308d6495181407a827ce595d44987f0
- Source dataset
- uspto-grants-1993_06
- Patent number
- US05223498
Reaction notes
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