Ethyl Acrylate → HCID 19755052, compound

HRID 1588951Notes

Reaction equation

HRID 1588951 reaction equation
[Na].Cl.Cl.[NH2:4][CH:5]1[CH:10]2[CH2:11][CH2:12][N:7]([CH2:8][CH2:9]2)[CH2:6]1.[C:13]([O:17][CH2:18][CH3:19])(=[O:16])[CH:14]=[CH2:15]>C(O)C>[CH2:18]([O:17][C:13](=[O:16])[CH2:14][CH2:15][NH:4][CH:5]1[CH:10]2[CH2:11][CH2:12][N:7]([CH2:8][CH2:9]2)[CH2:6]1)[CH3:19]

Participants

5

Reactant 3

HCID 8821Ethyl AcrylateHCID 197853Quinuclidine, 3-amino-, dihydrochlorideHCID 5360545Sodium

Product 1

HCID 19755052HCID 19755052, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

0.92 g (20 mmol) of sodium were dissolved in 100 ml of ethanol. 4.0 g (20 mmol) of 3-amino-quinuclidine dihydrochloride were added and the mixture was stirred for 5 minutes. 2 g (20 mmol) of ethyl acrylate were added, the mixture was boiled for 20 hours, and evaporated in vacuo. The residue was shaken with little water and methylene chloride. The organic layer was separated and evaporated in vacuo, giving 3.1. g of the desired product.

Workup

  1. waitthe mixture was boiled for 20 hours
  2. customevaporated in vacuo
  3. stirringThe residue was shaken with little water and methylene chloride
  4. customThe organic layer was separated
  5. customevaporated in vacuo
  6. customgiving 3.1

Sources & evidence

ORD record
ord-41f7560eb24f46f7a4e6f235d4c286e6
Source dataset
uspto-grants-1993_06
Patent number
US05223625

Reaction notes

Loading…