Phosgene → Morpholinium, 4-(chloromethylene)-, chloride

HRID 1589251Notes

Reaction equation

C([N:3]1[CH2:8][CH2:7][O:6][CH2:5][CH2:4]1)=O.[C:9]([Cl:12])([Cl:11])=O>>[Cl-:11].[Cl:12][CH:9]=[N+:3]1[CH2:8][CH2:7][O:6][CH2:5][CH2:4]1

Participants

Reactant 2

HCID 6371Phosgene

HCID 20417N-Formylmorpholine

Product 1

HCID 11355716Morpholinium, 4-(chloromethylene)-, chlorideYield 65.1%

Procedure

Utilizing a procedure similar that used in Preparation 1, but beginning with N-formylmorpholine (346 gm, 3.01 mol) and phosgene (301 gm, 3.05 mol), a 65% yield (333 gm, 1.96 mol) of N-(chloromethylene)-morpholinium chloride is obtained.

Workup

customthat used in Preparation 1

Sources & evidence

ORD record: ord-0eae75b19cb7441f88e22943d0a06e5c
Source dataset: uspto-grants-1986_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04568741

Reaction notes

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