Hydrochloric Acid → HCID 178492099, compound

HRID 1589406Notes

Reaction equation

HRID 1589406 reaction equation
[CH:1]([C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][N:4]=1)=[O:2].[CH3:9][O:10][C:11]1[C:12]([CH2:17][CH2:18][CH2:19][CH2:20][NH:21][C:22]2[NH:23][CH:24]=[CH:25][C:26](=[O:28])[N:27]=2)=[N:13][CH:14]=[CH:15][CH:16]=1.Cl>>[CH3:9][O:10][C:11]1[C:12]([CH2:17][CH2:18][CH2:19][CH2:20][NH:21][C:22]2[NH:23][CH:24]=[C:25]([CH:1]([C:3]3[CH:8]=[CH:7][CH:6]=[CH:5][N:4]=3)[OH:2])[C:26](=[O:28])[N:27]=2)=[N:13][CH:14]=[CH:15][CH:16]=1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 142732-PyridinecarboxaldehydeHCID 178492098HCID 178492098, compound

Product 1

HCID 178492099HCID 178492099, compound

Procedure

2-Formylpyridine is reacted with 2-(4-(3-methoxy-2-pyridyl)butylamino)-4(1H)-pyrimidinone in refluxing concentrated hydrochloric acid for 24 hours to give 2-(4-(3-methoxy-2-pyridyl)butylamino)-5-((2-pyridyl)hydroxymethyl)-4(1H)-pyrimidinone.

Sources & evidence

ORD record
ord-b27abe6cb773460c9f0bdfb72bc1e835
Source dataset
uspto-grants-1986_02
Patent number
US04569996

Reaction notes

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