Dimethylformamide → 1-{3-[4-(2-aminopyrimidin-4-yl)-1-(4-methoxybenzyl)-1H-pyrazol-3-yl]phenyl}-3-[4-(trifluoromethyl)phenyl]urea
Reaction equation
[CH3:42][N:43]([CH3:44])[CH:45]=[O:46].[F:29][C:30]([c:31]1[cH:32][cH:33][c:34]([N:37]=[C:38]=[O:39])[cH:35][cH:36]1)([F:40])[F:41].[NH2:1][c:2]1[cH:3][c:4](-[c:8]2[n:9][n:10]([CH2:20][c:21]3[cH:22][cH:23][c:24]([O:27][CH3:28])[cH:25][cH:26]3)[cH:11][c:12]2-[c:13]2[n:14][c:15]([NH2:19])[n:16][cH:17][cH:18]2)[cH:5][cH:6][cH:7]1>>[NH:1]([c:2]1[cH:3][c:4](-[c:8]2[n:9][n:10]([CH2:20][c:21]3[cH:22][cH:23][c:24]([O:27][CH3:28])[cH:25][cH:26]3)[cH:11][c:12]2-[c:13]2[n:14][c:15]([NH2:19])[n:16][cH:17][cH:18]2)[cH:5][cH:6][cH:7]1)[C:38]([NH:37][c:34]1[cH:33][cH:32][c:31]([C:30]([F:29])([F:40])[F:41])[cH:36][cH:35]1)=[O:39]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-ada26bb32940487b817f238d0c8a74f5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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