反应详情

In a test tube with an outer diameter of 15 mm, 0.25 g of a baker's yeast (Saccharomyces cerevisiae, manufactured by Oriental Kobo Kogyo K K ) was suspended in 3 ml of a McIlvaine buffer containing 0.54 g of glucose dissolved therein, and then 6 μl of dimethylformamide containing 6 mg of methyl 2-chloro-3-oxo-3-(p-methoxyphenyl)propionate was charged, followed by shaking reaction at 30° C. for 24 hours. When the reaction mixture was extracted with 2 ml of ethyl acetate and the amount of methyl 2-chloro-3-hydroxy-3-(p-methoxyphenyl)propionate formed was quantitated, it was found that 0.6 mg of the product was formed.

1. customIn a test tube with an outer diameter of 15 mm, 0.25 g of a baker's yeast (Saccharomyces cerevisiae, manufactured by Oriental Kobo Kogyo K K ) was suspended in 3 ml of a McIlvaine
2. dissolutiondissolved
3. customreaction at 30° C. for 24 hours
4. extractionWhen the reaction mixture was extracted with 2 ml of ethyl acetate