Methanol → HCID 58995814, compound

HRID 1591526Notes

Reaction equation

HRID 1591526 reaction equation
[CH:1]1[C:14]2[C:5](=[CH:6][C:7]3[C:12]([C:13]=2[C:15]2[NH:16][C:17]4[C:18]([N:31]=2)=[C:19]2[C:24](=[C:25]5[C:30]=4[CH:29]=[CH:28][CH:27]=[N:26]5)[N:23]=[CH:22][CH:21]=[CH:20]2)=[CH:11][CH:10]=[CH:9][CH:8]=3)[CH:4]=[CH:3][CH:2]=1.[H-].[Na+].I[CH3:35].CO>CN(C)C=O>[CH3:35][N:31]1[C:18]2[C:17](=[C:30]3[C:25](=[C:24]4[C:19]=2[CH:20]=[CH:21][CH:22]=[N:23]4)[N:26]=[CH:27][CH:28]=[CH:29]3)[N:16]=[C:15]1[C:13]1[C:12]2[C:7]([CH:6]=[C:5]3[C:14]=1[CH:1]=[CH:2][CH:3]=[CH:4]3)=[CH:8][CH:9]=[CH:10][CH:11]=2

Participants

6

Reactant 4

HCID 887MethanolHCID 6328Methyl iodideHCID 24758Sodium hydrideHCID 60132550HCID 60132550, compound

Product 1

HCID 58995814HCID 58995814, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Conditions

Temperature
23 °C

Procedure

A mixture of the 2-(9-anthryl)imidazo[4,5-f]-[1,10]phenanthroline (10 grams) and sodium hydride (11.5 grams) in 300 milliliters of dimethylformamide was stirred at ambient temperature (about 23° C.) for 30 minutes. Into the resulting mixture was added 18.7 grams of iodomethane. The reaction was stirred overnight at room temperature when 100 milliliters of methanol was added. The precipitate was collected by filtration, washed with water, and dried in a vacuum oven to give the crude product which was further purified by sublimation. The product and its structure was confirmed by proton NMR analysis.

Workup

  1. additionwas added
  2. filtrationThe precipitate was collected by filtration
  3. washwashed with water
  4. customdried in a vacuum oven

Sources & evidence

ORD record
ord-295b6fcc0923456cbe6da98a5566c179
Source dataset
uspto-grants-2007_11
Patent number
US07291404B2

Reaction notes

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