N-Methylethylenediamine → HCID 69423830, compound

HRID 1591760Notes

Reaction equation

[C:1]([C:3]1[CH:8]=[CH:7][C:6]([CH2:9][CH2:10][N:11]([CH3:30])[C:12](=[O:29])[CH2:13][CH2:14][CH2:15][NH:16][CH2:17][S:18]([C:21]2[CH:26]=[CH:25][CH:24]=[C:23]([Cl:27])[C:22]=2[Cl:28])(=[O:20])=[O:19])=[CH:5][CH:4]=1)#[N:2].[S].[CH3:32][NH:33][CH2:34][CH2:35]N>>[Cl:28][C:22]1[C:23]([Cl:27])=[CH:24][CH:25]=[CH:26][C:21]=1[S:18]([CH2:17][NH:16][CH2:15][CH2:14][CH2:13][C:12]([N:11]([CH3:30])[CH2:10][CH2:9][C:6]1[CH:5]=[CH:4][C:3]([C:1]2[N:33]([CH3:32])[CH2:34][CH2:35][N:2]=2)=[CH:8][CH:7]=1)=[O:29])(=[O:20])=[O:19]

Participants

Reactant 3

HCID 8014N-Methylethylenediamine

HCID 5362487Sulfur

HCID 69424047HCID 69424047, compound

Product 1

HCID 69423830HCID 69423830, compound

Procedure

Analogously to 13b), 4-[(2,3-dichlorobenzenesulphonyl)methylamino]-N-methyl-N-{2-[4-(1-methyl-4,5-dihydro-1H-imidazol-2-yl)phenyl]ethyl}butyramide was prepared from 0.62 g (1.32 mmol) of N-[2-(4-cyanophenyl)ethyl]-4-[(2,3-dichlorobenzenesulphonyl)methylamino]-N-methylbutyramide, 48 mg (1.49 mmol) of sulphur and 3 ml of N-methylethylenediamine.

Sources & evidence

ORD record: ord-a97933081dc94a6cb31b3b5ceec8bbe3
Source dataset: uspto-grants-2007_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07291642B2

Reaction notes

Loading…