huagongshe.com
HRID1593197

反应详情

EQUATION

反应方程式

HRID 1593197 的结构方程式

REACTANTS

反应物

4
结构：COC(=O)CC(C)=O
HCID7757

Methyl acetoacetate

C5H8O3

结构：N[C@@H]1CCCC[C@H]1O
HCID735777

(1R,2R)-2-Aminocyclohexanol

C6H13NO

结构：O=C(CBr)c1cc(C(F)(F)F)ccc1Cl
HCID2783183

未命名化合物

结构：NC[C@H]1CCCC[C@H]1O
HCID12483365

未命名化合物

PRODUCTS

生成物

1
结构：Cc1c(C(=O)N[C@@H]2CCCC[C@H]2O)cc(-c2cc(C(F)(F)F)ccc2Cl)n1CC1CCCCC1O
HCID58999090

未命名化合物

PROCEDURE

实验过程

The title compound was synthesized in analogy to Example 68, using 3-oxo-butyric acid methyl ester as compound of formula R, 2-bromo-1-(2-chloro-5-trifluoromethyl-phenyl)-ethanone as compound of formula S, cis-2-aminomethyl-1-cyclohexanol as R3—(CH2)m—NH2 and (1R,2R)-2-amino-cyclohexanol as R1R2NH, MS (ISP) 513.5 (M+H)+