2-Chloroethyl methyl ether → HCID 22927120, compound

HRID 1593347Notes

Reaction equation

HRID 1593347 reaction equation
[CH2:1]([P:3]([CH2:6][CH3:7])[CH2:4][CH3:5])[CH3:2].[CH3:8][O:9][CH2:10][CH2:11][Cl:12]>C1(C)C=CC=CC=1>[Cl-:12].[CH3:8][O:9][CH2:10][CH2:11][P+:3]([CH2:6][CH3:7])([CH2:4][CH3:5])[CH2:1][CH3:2]

Participants

4

Reactant 2

HCID 123162-Chloroethyl methyl etherHCID 27365Triethylphosphine

Product 1

HCID 22927120HCID 22927120, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

First, 200 ml of a toluene solution of triethylphosphine (triethylphosphine content, approx. 20%; product of Kanto Chemical) was mixed with 50 ml of 2-methoxyethyl chloride (Kanto Chemical) to effect a reaction, which was carried out under refluxing for 24 hours. The solvent was then distilled off at normal pressure, following which the remaining solvent and unreacted reagents were completed removed by distillation using a vacuum pump. The residue was recrystallized from an ethanol-THF system, yielding 45 g of 2-methoxyethyltriethylphosphonium chloride.

Workup

  1. customa reaction, which
  2. temperatureunder refluxing for 24 hours
  3. distillationThe solvent was then distilled off at normal pressure
  4. customwere completed removed by distillation
  5. customThe residue was recrystallized from an ethanol-THF system

Sources & evidence

ORD record
ord-7e5decf6d84343b7ad8f1ca6a78d6759
Source dataset
uspto-grants-2007_11
Patent number
US07297289B2

Reaction notes

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