Phenethylamine → 1-Methyl-1,2,3,4-tetrahydroisoquinoline

HRID 159402Notes

Reaction equation

HRID 159402 reaction equation
[CH2:1]([CH2:2][c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1)[NH2:9].[CH3:10][CH2:11][N:12]([CH2:13][CH3:14])[CH2:15][CH3:16].[CH3:17][C:18](=[O:19])[Cl:20].[Cl:21][CH2:22][Cl:23]>>[CH2:1]1[CH2:2][c:3]2[cH:4][cH:5][cH:6][cH:7][c:8]2[CH:11]([CH3:10])[NH:9]1

Participants

5

Reactant 4

HCID 1001PhenethylamineHCID 6344DichloromethaneHCID 6367Acetyl chlorideHCID 8471Triethylamine

Product 1

HCID 922141-Methyl-1,2,3,4-tetrahydroisoquinoline

Sources & evidence

ORD record
ord-48eb25e2bcb64a97aae60173466ba91f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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